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Table 2 LB type pathology in PA patient’s postmortem brain

From: Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

Brain area

LB type pathology

Brainstem lesion

IX-X

+++

LC

+++

SN

++

Basal forebrain/Limbic

nbM

++

Amy

++

Ent

+

Cing

+

Neocortical

T

-

F

-

 

P

-

  1. IX-X, motor cranial nerves IX-X; LC, Locus Coeruleus; SN, Substantia Nigra; nbM, nucleus basal of Meynert; Amy, Amygdala; Ent, Entorhinal cortex; T, Temporal lobe; F, Frontal lobe; P, Parietal lobe.
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Molecular Brain

ISSN: 1756-6606