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Table 1 Functional classification on the basis of the gene ontology (GO) terms

From: Rapid and stable changes in maturation-related phenotypes of the adult hippocampal neurons by electroconvulsive treatment

Increased change by both ECS- and SSRI-treatment (660 probes)

GO number

GO term

No.

P value

GO:0008203

cholesterol metabolic process

16

9.8E-09

GO:0016126

sterol biosynthetic process

10

1.1E-08

GO:0008202

steroid metabolic process

15

3.5E-08

GO:0006695

cholesterol biosynthetic process

9

1.3E-06

GO:0006694

steroid biosynthetic process

11

4.4E-06

GO:0007399

nervous system development

26

2.1E-05

GO:0010977

negative regulation of neuron projection development

10

4.1E-05

GO:0061564

axon development

5

5.3E-05

GO:0010976

positive regulation of neuron projection development

14

7.6E-05

GO:0042493

response to drug

24

1.2E-04

GO:0051591

response to cAMP

9

1.4E-04

GO:0009790

embryo development

10

2.2E-04

GO:0006950

response to stress

7

2.3E-04

GO:0001649

osteoblast differentiation

12

2.4E-04

GO:0031668

cellular response to extracellular stimulus

6

2.8E-04

GO:0034097

response to cytokine

10

3.5E-04

GO:0007568

aging

15

3.6E-04

GO:0030154

cell differentiation

38

3.8E-04

GO:0009968

negative regulation of signal transduction

8

4.4E-04

GO:0007155

cell adhesion

27

4.9E-04

GO:0006629

lipid metabolic process

26

5.1E-04

GO:0007565

female pregnancy

10

5.4E-04

GO:0043065

positive regulation of apoptotic process

21

6.1E-04

GO:0043627

response to estrogen

9

7.6E-04

GO:0007179

transforming growth factor beta receptor signaling pathway

9

8.3E-04

GO:0043407

negative regulation of MAP kinase activity

7

8.4E-04

GO:2001237

negative regulation of extrinsic apoptotic signaling pathway

7

9.5E-04

GO:0010628

positive regulation of gene expression

23

9.6E-04

  1. The gene probes (660 probes) showed significantly increased change by both ECS- and SSRI-treatment were selected. P-value was calculated by a modified Fisher’s exact test. Highly associated gene ontology terms (P < 0.001) were represented