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Fig. 1 | Molecular Brain

Fig. 1

From: Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein

Fig. 1

iDG-like molecular phenotypes in the hippocampus of P123H βS Tg mice. a Results of quantitative PCR. Bar graphs represent relative mRNA expression levels normalized to β-actin mRNA. Data obtained from two independent experiments were combined and shown as the mean ± SEM. (n = 8 for wild-type mice and n = 10 for P123H βS Tg mice). *P < 0.05, **P < 0.01 versus wild-type mice. bd Representative images (left panels) and the semi-quantitative results (right panels) of immunofluorescence imaging of Calb1 (b), Gria1 (c), and Iba1 (d) in the DG of wild-type and P123H βS Tg mice. Higher magnification of the boxed area is shown below the corresponding panel (b). Data are shown as the mean ± SEM (n = 4 for each genotype). *P < 0.05, **P < 0.01 versus wild-type mice. Scale bars, 200 μm (b, d) and 500 μm (c). g, granule cell layer; h, hilus; m, molecular layer

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