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Fig. 3 | Molecular Brain

Fig. 3

From: Leptin down-regulates KCC2 activity and controls chloride homeostasis in the neonatal rat hippocampus

Fig. 3

The action of leptin of chloride homeostasis is developmentally regulated. a Box plots of ∆EGABA induced by leptin (100 nM, 20 min) at postnatal (P) day 2, 5 and 10. b Plots of mean and standard error to the mean of the ∆EGABA induced by leptin (100 nM, 20 min) versus the reversal potential of GABAA receptor-mediated postsynaptic currents (EGABA) at P2, P5 and P10. c Box plots of leptin action (100 nM, 20 min) on spike activity at P5 and P10. #P < 0.05 when compared to pre-leptin values, two-tailed Wilcoxon paired test. *P < 0.05 when compared to leptin response at P5, two-tailed Mann Whitney test

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