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Fig. 1 | Molecular Brain

Fig. 1

From: Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis

Fig. 1

Burden of five specific RC-L1 loci in healthy controls and individuals with SALS. a Percentage of male individuals harbouring different numbers of specific RC-L1 present alleles of the polymorphic L1 loci listed in Table 1 was determined by using tagging SNPs as a proxy for the L1 genotype in controls and SALS patients. In males, it is possible to have up to 9 alleles with a RC-L1 present of the 5 loci genotyped. b Percentage of female individuals harbouring different numbers of RC-L1 present alleles of the polymorphic L1 loci listed in Table 1 was determined by using tagging SNPs as a proxy for L1 genotype in controls and SALS. In females, it is possible to have up to 10 alleles with a RC-L1 present of the 5 loci genotyped. Two-sample test for equality of proportions to compare number of RC-L1 between cases and controls. Male-Controls n = 117, SALS n = 616, Female—Controls n = 187, SALS n = 400

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Molecular Brain

ISSN: 1756-6606