Fig. 4
From: Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice
Histology and stereological quantification of TH neurons in the substantia nigra (SN). a Representative images of TH-positive neurons in the NTg (left) and Tg (right) SN from 22-months-old mice. Anti-TH antibody was used for staining. ×10 magnification. Scale bar 500 µm. b Stereological counting of TH-positive neurons in the NTg and Tg mouse SN (mean ± SEM). 7 brain sections from each mouse were used for the unbiased stereological analysis. ×63 magnification. No significant difference (P = 0.136) in the number of TH-positive neurons in the SN was observed between NTg mice (n = 5) and Tg controls (n = 5); Student’s t-test