Skip to main content

Table 1 Regions showing significantly different functional connectivity with the medial hypothalamus (MH) and lateral hypothalamus (LH) in fibromyalgia patients (FM) and healthy controls, before and after three-month intervention

From: Altered functional connectivity between hypothalamus and limbic system in fibromyalgia

Seed

Condition

Region

Cluster size

MNI coordinates

Peak z value

X

Y

Z

MH

FM (pre) > HC

Bilateral subcallosal cingulate gyrus

125

− 12

14

− 16

3.85

 

HC > FM (pre)

Bilateral cerebellum

155

0

− 80

− 28

3.82

  

Left amygdala

70

− 30

− 8

− 16

4.72

  

Right amygdala

23

32

− 8

− 20

3.12

  

Right thalamus

32

10

− 14

0

3.54

 

FM (post) > FM (pre)

Right DLPFC/operculum

105

56

20

2

4.16

 

Right occipital gyrus

180

22

− 78

− 6

4.23

 

Left cerebellum

101

− 12

− 70

− 20

3.96

 

Left amygdala

24

− 18

− 12

− 12

3.64

 

Right thalamus

59

8

− 18

2

4.19

 

Left rACC

23

− 12

44

22

3.8

 

FM (pre) > FM (post)

None

     

LH

FM (pre) > HC

Right temporal pole

152

38

6

− 42

3.54

 

HC > FM (pre)

Right inferior occipital gyrus/cerebellum

213

40

− 66

− 8

3.93

 

FM (post) > FM (pre)

Bilateral rACC

229

10

36

6

4.42

  

Bilateral MPFC

180

8

46

− 2

4.1

  

Right middle temporal gyrus/superior temporal gyrus

185

60

0

− 16

4.34

  

Left PCC

106

− 12

− 36

34

4.09

 

FM (pre) > FM (post)

None

     
  1. Cluster size indicates the number of voxels in the cluster; the size of each voxel is 8 mm3
  2. FM (pre) fibromyalgia pre-Tai Chi intervention, FM (post) fibromyalgia post-Tai Chi intervention, HC healthy control, DLPFC dorsolateral prefrontal cortex, PAG periaqueductal gray, rACC rostral anterior cingulate cortex, MPFC medial prefrontal cortex, PCC posterior cingulate cortex