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Fig. 2 | Molecular Brain

Fig. 2

From: Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis

Fig. 2

FMRP mRNA targets identified from the RIP-seq of the WT E14.5 cortex. a RIP-seq workflow. b Scatterplot comparing log2 ratios of significant (q < 0.01) FPKM expressions values of FMRP-IP and IgG-IP. The vertical coordinates represent the log2-FPKM + 1 values for each gene from FMRP-IP, and the horizontal coordinates represent the log2-FPKM + 1 values for each gene IgG-IP. Highlighted in blue are the 865 FMRP target genes selected based on gene expression values, log2FC > 1, and FPKM > 10 for the FMRP-IP. c The top 10 GO (biological process) terms enriched in the 865 FMRP target genes

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