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Table 2 Summary of exploratory behaviors in the open-field test

From: Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice

 

Gad1+/+

Gad1tTA/STOP−tetO

t values

p values

Total distance (cm)

2434.4 ± 102.7

3495.0 ± 179.7

5.389

 < 0.001

Total duration of movement (s)

166.8 ± 4.9

185.7 ± 5.5

2.235

0.036

Total number of movement episode

95.4 ± 2.1

86.7 ± 2.6

2.330

0.029

Moving speed (cm/s)

13.1 ± 0.3

17.8 ± 0.7

6.784

 < 0.001

Distance per movement (cm)

23.4 ± 1.3

38.7 ± 3.1

5.380

 < 0.001

Duration per movement (s)

1.8 ± 0.1

2.2 ± 0.1

3.295

0.003

Time spent in the wall side (s)

246.9 ± 5.5

271.6 ± 5.3

2.671

0.014

Time spent in the center region (s)

53.1 ± 5.5

28.4 ± 5.3

2.671

0.014

% Time spent in the center region

17.7 ± 1.8

9.5 ± 1.8

2.670

0.014

  1. Exploratory behaviors were measured for 5 min in the open-field in Dox-treated Gad1+/+ (n = 17) and Gad1tTA/STOP−tetO (n = 7) mice. Data represent the mean ± SE. A p value less than 0.05 was considered a significant difference (Student’s t-test)