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Table 2 Verification of differentially expressed proteins after TBI by PRM

From: iTRAQ-based proteomic profiling reveals protein alterations after traumatic brain injury and supports thyroxine as a potential treatment

Accession

Gene name

Average total normalized area

Fold change

p-value

Sham

TBI

A0A0G2JSK1

Serpina3c

587,193.8154

967,199.9746

1.65

0.0010

A0A0G2JZ73

Serpina1

358,594,583.9

661,025,493

1.84

< 0.0001

A0A0H2UHI5

Serpina3n

15,925,972.06

30,105,445.75

1.89

< 0.0001

D3ZJF8

Fcgbp

492,977,070

364,252,286

0.74

0.00020

F1LRV4

Hspa4

315,888,493.8

319,391,993

1.01

0.48

G3V9R9

Afm

9,171,981.438

6,262,567.344

0.68

0.058

M0RBF1

C3

33,341,743.73

88,878,077.44

2.66

< 0.0001

P01946

Hba1

859,325,340.5

3,225,272,654

3.75

< 0.0001

P02091

Hbb

2,007,838,409

6,847,982,715

3.41

< 0.0001

P02767

Ttr

152,664,429.5

274,579,978.7

1.80

< 0.0001

P02770

Alb

1,334,438,359

1,462,217,836

1.10

0.099

P11517

Hbb2

1,987,823,049

6,870,701,039

3.46

< 0.0001

P20059

Hpx

81,400,524.38

143,040,114.8

1.76

< 0.0001

P20156

Vgf

17,525,134.63

28,274,163.63

1.61

< 0.0001

P24090

Ahsg

11,552,915.97

25,108,376.28

2.17

< 0.0001

P42930

Hspb1

5,132,833.438

18,194,532.5

3.54

< 0.0001

Q03626

Mug1

70,921,905.59

149,480,671.3

2.11

< 0.0001

Q62669

LOC103694855

487,524,419.4

1,385,746,698

2.84

< 0.0001

Q63041

A1m

9,261,727.438

18,843,111.94

2.03

< 0.0001

Q6IFU7

Krt42

40,789,820

35,523,088.63

0.87

0.31

Q6IFV1

Krt14

927,194,854

778,350,430.6

0.84

0.00030

Q6IMF3

Krt1

1,326,149,813

947,186,885.5

0.71

< 0.0001

Q6P6Q2

Krt5

623,317,271.3

427,289,138.7

0.69

0.0095

  1. TBI traumatic brain injury; PRM parallel reaction monitoring