Table 1 Comprehensive behavioral test battery in Trpm1^−/− mice

General health/neurological screen

11–12

Grip strength/wire hang test

11–12

Light/dark transition (Dark box start)

11–12

Open field

11–12

Elevated plus maze

12–13

Hot plate

12–13

Social interaction (novel environment)

12–13

Rotarod

12–13

Social approach and novelty preference (Crawley’s ver.)

13–14

Acoustic startle response and prepulse inhibition

13–14

Porsolt forced swim

15–16

Gait analysis

16–17

Barnes maze_Training

20–23

Barnes maze_PT1(24 h)

22–23

Barnes maze_PT2 (1 M)

27–28

T-maze spontaneous alternation

31–32

Light/dark transition (Light box start)

34–35

Tail suspension

34–35

Contextual and cued fear conditioning_Day1 (conditioning)

34–35

Contextual and cued fear conditioning_Day2 (context and cued)

34–35

Contextual and cued fear conditioning_Day30 (remote memory)

38–39

Wire hang test_2nd

38–39

Social interaction in home cage

39–40

Home cage test (daily activity)

40–43

Open field test + MPH (10 mg/kg)

74–75

Open field test + MPH (3 mg/kg)

79–81