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Fig. 2 | Molecular Brain

Fig. 2

From: The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

Fig. 2

C. elegans TMEM-132 is crucial for proper morphology of the PDE neuron. a–d Confocal fluorescence images showing indicated major categories of abnormal morphology of PDE neurons in tmem-132 deficient C. elegans. e Quantification of percentage of animals with abnormal PDE neuronal morphology in each indicated category shown in pie charts. f Table summarizing overall percentage of animals with normal PDE neuronal morphology in wild type and tmem-132 mutants, including those carrying two independent deletion alleles, the P784T knock-in allele and the Q780X nonsense allele that truncates the C-terminus of TMEM-132. All strains carry the PDE reporter osm-6p::GFP and were outcrossed to minimize potential effects of background mutations. Scale bars: 5 µm

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