Fig. 3
From: SGTA associates with intracellular aggregates in neurodegenerative diseases
SGTA interacted with glial cytoplasmic inclusions (GCIs) in multiple system atrophy (MSA). a Immunohistochemistry of postmortem tissue with anti-SGTA antibody in the substantia nigra of PD patients, in the medulla of MSA patients, in the spinal cord of ALS patients, and in the pontine nucleus of control patients. Control patients: scale bar = 20 μm, others: scale bar = 50 μm. Note that intense staining observed in the substantia nigra of PD patients represents the melanin pigments. Arrow heads indicate SGTA staining of GCIs in oligodendrocytes. b Double fluorescence immunohistochemistry labeling with anti-phosphorylated α-synuclein antibody (green) and anti-SGTA antibody (red) in the medulla of a patient with MSA. Scale bar = 50 μm