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Fig. 6 | Molecular Brain

Fig. 6

From: Two novel mouse models mimicking minor deletions in 22q11.2 deletion syndrome revealed the contribution of each deleted region to psychiatric disorders

Fig. 6

Contextual and cued fear-conditioning test. a Fear-conditioning test of Del(1.4 Mb)/+ mice (n = 12 for WT; n = 12 for Del(1.4 Mb)/+ mice). Context-dependent freezing response (%) towards the tone and foot-shock paring (conditioning) measured 24 h after the initial exposure (left panel). Cued-dependent freezing response (%) measured 48 h after the conditioning (right panel). b Fear-conditioning test of Del(1.5 Mb)/+ mice (n = 11 for WT; n = 12 for Del(1.5 Mb)/+ mice). Context-dependent freezing response (%) (left panel). Cued-dependent freezing response (%) (right panel). Data are expressed as mean ± SEM. n.s. not significant; ***p < 0.001

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Molecular Brain

ISSN: 1756-6606