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Fig. 6 | Molecular Brain

Fig. 6

From: Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity

Fig. 6

Reducing phosphorylated ERK1/2 level rescued spatial memory impairment of Prdx6−/− mice. a MEK inhibitor (U0126) injection before probe test. b Escape latency to platform and c mean swimming velocity during visible platform trial (n = 10–12 mice/group). d Learning curve during 5 days of training. e Percent time spent in each quadrant during the probe test. All data are presented as mean ± SEM. #p < 0.05, two-way measure ANOVA followed by Bonferroni’s post hoc test with one-way ANOVA for multiple comparison of percent time spent in target quadrant

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