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Fig. 4 | Molecular Brain

Fig. 4

From: Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis

Fig. 4

Ablation of IL-19 modulates microglial phenotype in SOD1G93A Tg at the late stage. Images of lumbar spinal cord of 20-week-old (a) SOD1G93ATg mice and (b) IL-19−/−/SOD1G93A Tg mice immunostained for CD68 (green) and Iba1 (red). Images of lumbar spinal cord of 20-week-old (c) SOD1G93A Tg mice and (d) IL-19−/−/SOD1G93A Tg mice immunostained for arginase 1 (green) and Iba1 (red). e Percentage of CD68 positive cells in Iba1 positive cells in lumbar spinal cord sections. f Percentage of arginase 1 positive cells in Iba1 positive cells in the lumbar spinal cord sections. Scale bars: 200 µm in merged images and 50 µm in enlarged images. Values are means ± SD. *p < 0.05

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