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Fig. 4 | Molecular Brain

Fig. 4

From: Meningitic Escherichia coli α-hemolysin aggravates blood–brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling

Fig. 4

Meningitic E. coli infection attenuated the hedgehog signaling in BMECs. A The expression of Gli2 on BMECs of the challenged mice via IF. The BMECs were marked with CD31 in green. White triangles indicated Gli2 in BMECs. Scale bars indicated 50 μm. B Expression alterations of Gli1 and Gli2 in hBMECs along with RS218 infection via qPCR and Western blot, and the subcellular localization of Gli1 in hBMECs 2 h post infection. **p < 0.01. The qPCR assays were performed in triplicates, and results were presented as mean ± SEM

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Molecular Brain

ISSN: 1756-6606