Skip to main content
Fig. 4 | Molecular Brain

Fig. 4

From: Transcriptomic profiling of high- and low-spiking regions reveals novel epileptogenic mechanisms in focal cortical dysplasia type II patients

Fig. 4

Differential gene expression in FCD type II patients. The PCA analysis and heatmap was generated using ClustVis. For Peer Review Singular value decomposition with imputation was used to calculate the PCs with maximum variance explained by PC1 (89.2% and 85.5% respectively). Plotting of the first two PCs (PC1 and PC2) segregated FCD MAX and control samples; and FCD MIN and FCD MAX samples into distinct clusters. Unit variance scaling is applied to rows containing the log-normalized counts of differentially expressed genes (padj1) and the columns are clustered using correlation distance and average linkage in the heatmap

Back to article page

Molecular Brain

ISSN: 1756-6606