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Fig. 4 | Molecular Brain

Fig. 4

From: Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents

Fig. 4

MeCP2 binds to GRIA1 and GRID1 promoters. ChIP was performed using anti-MeCP2 antibodies on sheared chromatin from SH-SY5Y neuroblastoma cells expressing MeCP2 on days 0, 2, 4, and 6. Purified DNA from immunoprecipitated chromatin was amplified using optimized primers for the promoters (GRIA1, GRID1, and GRIN1). Molecular weight markers are on the left in bases. Normal rabbit IgG was used as a negative immunoprecipitation control. +DNA: Purified chromosomal DNA, used as a positive control

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