Fig. 5From: PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferationReduced progenitor cells in PAK1 KO mice. Coronal brain sections of WT and PAK1 KO E14.5 embryos were stained for the active form of caspase 3 (CC3) or Pax6. a, b CC3 (red) and DAPI (blue) staining of WT (a) and PAK1 KO mice (b). c Summary graph of CC3 positive cells showing no differences between WT and PAK1 KO mice. d-g Pax6 (red) and DAPI (blue) staining of WT (d, f) and PAK1 KO mice (e, g). h Summary graph showing significantly decreased numbers of Pax6 positive cells PAK1 KO mice compared to their WT littermates. ***p < 0.001. Scale bars: 100 μmBack to article page