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Fig. 4 | Molecular Brain

Fig. 4

From: Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses

Fig. 4

GluA1, GluA2 and IP3R are decreased in SPKO. (A). Representative immunoblot and quantification of total (left) GluA1 and (right) GluA2 from hippocampi of WT (n = 5) and SPKO (n = 5) mice. (B, C). Representative images and quantification of CA1 pyramidal neuron tertiary dendrites immunostained with surface GluA1 antibody (WT n = 12, KO n = 14 slices) and surface GluA2 antibody (WT n = 13, KO n = 11 slices) in acute hippocampal slices. Scale bar = 3 μm. (D). Representative immunoblot and quantification of total (left) GluN2A and (right) GluN2B from hippocampi of WT (n = 5) and SPKO (n = 5) mice. (E). Representative immunoblot and quantification of total IP3R from hippocampi of WT (n = 8) and SPKO (n = 8) mice

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